Status : Active
Ethics Number : 2002/7/118
Lay Summary :
Diabetes is a major cause of morbidity and mortality and has been estimated to account for 10% of NHS spending and this is likely to increase. Therefore, understanding how to prevent complications is a major health priority, and looking at people who do NOT have diabetes, and its asscoiated complications, is an effective way to identfy factors that mean some people go on to develop complications and others do not.
To do this, we need to compile a large community database of people with diabetes in the South West region, and collect updated clinical and genetic information on their diabetes. Both genetic susceptibility and environment are involved in the development of complications involving the small blood vessels such as retinopathy and large vessels such as myocardial infarction and stroke. Each risk factor has its own genetic and environmental determinants.
Recruitment Target : 4000 with diabetes; 1000 controls
Start Date : 12/09/2007
End Date : 31/7/2017
DRN Number : DRN082
Publications Arising :
External Funding : Wellcome Trust, National Institute for Health Research