NIHR Exeter CRF Portfolio April 2015 - March 2016

CRF-Managed Recruiting Studies

Code

Study Title

Ethics/R&D Date of 1st Recruit
Intensity
Score
Status Q1 Q2 Q3 Q4 Total Samples Provided
CRF012 DARE (Diabetes Alliance Research in England) (Prof Andrew Hattersley)

R&D 2002/7/118  (29/08/02), REC 2002/7/118  (13/08/02)NIHR network adopted

16/08/07 3 Active 365 347 350
CRF018b ECHO PIV (Dr Kuni Aizawa) R&D 1004364(01/03/10), REC 09/H0202/49  (03/08/09) NIHR network adopted 05/07/10 6 Closed to recruitment - in follow up 0 0 0
CRF021 EXTEND (Prof Andrew Hattersley) R&D 1006386 (04/11/09), REC 09/H0106/75 (02/11/09) 11/01/10 4 Active 325 248 302
CRF033 OMENTALS (Dr Jacqueline Whatmore) R&D 2003/2/26 (24/03/03), REC 2003/2/26 (18/03/03) 02/12/03 Active 7 2 5
CRF053a Systematic microvascular disease in MVO R&D 1005379 (06/04/10), REC 09/H0206/56 (01/03/10) 08/07/10 5 Suspended 0 0 0
CRF067 ECHO-FMD (Dr Kuni Aizawa) R&D 1114486 (16/07/2010), REC 10/H0203/29 (12/04/2013) 28/11/2011 Active 20 21 12
CRF072 PROMOTE (Nicola Edge) R&D 1504074 (21/10/14), REC 14/EE/1108 (29/08/14).  NIHR network adopted 03/11/14 Active 27 31 34
CRF078 Hypothyroidism in pregnancy (DR Bijay Vaidya) R&D 1122566 (11/08/11), REC 11/SW/0088 (03/08/11) 18/08/11 1 Closed 42 13 0 0 55
CRF079 Royal Devon & Exeter Tissue Bank (Mr Malcolm Crundwell) R&D 1204632 (11/04/11), REC 11/SW/0018 (11/04/11) 06/06/11 4 Active 7 6 10
CRF087 Predicting Adverse Events (Dr Tariq Ahmad) R&D 1206654 (07/12/11), REC 11/SW/0222 (01/12/13) NIHR network adopted 23/12/11 Coordinating Centre Active 12 3 11
CRF095 Intermittent Impulse Compression Study (Dr Clare Thorn) R&D 1208687 (13/02/12), REC 11/SW/0320 (26/01/12) 22/03/12 Active 0 0 0
CRF102 DIRECT 3.3 (GLP-1) (Prof Andrew Hattersley) R&D 1301729 (16/05/12), REC 11/ES/0046 (23/01/12).  NIHR network adopted 30/05/12 Closed 7 0 0 0 7
CRF103 DIRECT 2.2 (Prof Andrew Hattersley) R&D 1304765 (26/09/12), REC 12/NE/0132 (15/05/12).  NIHR network adopted 12/10/12 Closed to recruitment (FU visits only) 0 0 0 0 0
CRF110 Genetic Beta Cell Research Bank (Prof Sian Ellard) R&D 1308826 (20/05/13), REC 12/WA/0225 (19/11/12) 20/05/13 1 Active 67 70 105
CRF112 ProMaster (Prof Andrew Hattersley) R&D 1309831 (23/03/13), REC 12/SW/0347 (18/01/13) NIHR network adopted 28/03/13 3 Closed to recruitment - in follow up 7 0 0 0 7
CRF115 Exome Seq in POI (Dr Anna Murray) R&D 1305789 (15/03/13), REC 12/SW/0240 (23/01/13) 19/03/13 1 Active 0 0 3
CRF118 Renal Denervation- pilot (Dr Andrew Sharp) R&D 1305780 (04/12/12), REC 12/SW/0265(14/11/12) 18/12/12 2
Active
0 0 0
CRF119 GATE Genetics of Apetite (Prof Tim Frayling) R&D 1308825 (07/12/12), REC 12/NW/0858 (20/11/12) 10/12/12 1 Active 4 220 15
CRF120 C. Diff study (STB08) (Dr Ray Sheridan)- samples only) R&D 5/008 STB08 (03/10/12), REC STB08 (06/08/12) 28/02/13 1 Active 7 4 2
CRF121 HARC (Dr Rhian Clissold) R&D 1307804 (07/01/13), REC 12/SW/0325 (03/01/13) NIHR network adopted 31/01/13 1 On hold 3 2 1 0 6
CRF128 PANTS (Dr Tariq Ahmad) R&D 1307805 (06/02/13), REC 12/SW/0323 (23/01/13) NIHR network adopted 08/02/13 Coordinating centre Active 6 10 9
CRF133 PRDS (Dr Andrew Sharp) R&D 1312876 (19/07/13), REC 13/SW/0085 (03/06/13) In set-up 0 0 0
CRF135 iDEND (Dr ALi Chakera) R&D 1311863 (05/09/13), REC 13/SW/0114 29/11/2013 Active 0 0 0
CRF140 PTRB (Peninsula Pre/Perinatal Twins Research Bank) (Dr Bea Knight) R&D 1503072 (7/001) /CPTRB1 (16/07/14), REC 13/SW0249 (23/12/13)

 

2

Active 18 15 16
CRF142 TIGI (Type 1 genetic insulin production) (DR Richard Oram) R&D 1407957(21/01/14), REC 13/SW/0312  (24/01/14). NIHR network adopted 24/02/14 Active 27 34 34
CRF148 Genetic Factors of Inflammatory Bowel Disease (Dr Tariq Ahmad) R&D 1204632  (5/011) STB11 (02/10/13), REC STB11 (10/09/13) 17/03/14 1 Active 0 0 0
CRF149 Video rate blood flow imaging for reconstructive plastic surgery (Dr Andrew Wilson) R&D 1406944 (21/11/13), REC 13/SW/0289 (18/11/13) 12/12/13 Active 4 3 3
CRF154 CARMELINA (Dr Bijay Vaidya) R&D 1404921 (23/12/13), REC 13/NW/0692 (08/11/13). NIHR network adopted 12/02/14 1 Active 1 1 1
CRF155 Molecular genetics of human birth defects (Prof Andrew Hattersley) R&D 1411003 (12/03/14), REC 08/80713/82 (15/10/08) NIHR network adopted 14/04/14 Active 0 0 5
CRF157 The relationship between renal nitrate clearance and eGFR (Dr Richard D.Souza) R&D 1409992 (12/05/14), REC 14/SW/0041 (09/05/14) 29/05/14 Active 6 5 3
CRF158 What is the best collection method to measure albumin in urine? (Kim Gooding) R&D 1411014 (08/04/14), REC 14/SW/0049 (03/04/14) 06/05/14 Active 5 1 1
CRF159 Dietary Nitrate in Anaemia (Dr Paul Kerr) R&D 1404914 (10/09/14), REC 14/SW/0081 (27/08/14) 06/10/14 Active 8 5 1
CRF160 Yo-yo dieting (Dr Katarina Kos) R&D 1411005 (10/06/14), REC 14/SW/0101 27/07/14 Active 3 1 6
CRF161 Cartilage from TKR (STB13) (Peter Winlove) R&D 5/013 STB13 (30/12/13), REC STB13 (03/12/13) 27/02/14 1 Closed to recruitment 4 11 0 0 15
CRF162 Involvement of GLP-1 receptor on GLP-1 analogues’ mediated microvascular function in humans, in vivo (Kim Gooding) R&D 1412018 (01/07/14), REC 14/SW/0093 (26/06/14) In set-up 0 0 0
CRF165 GLP1 ADDS tissue collection (Dr Katarina Kos) R&D 5/014 STB014 (04/04/14), REC STB014 (27/03/14) 16/07/14 Closed 0 0 0 0 0
CRF166 StartRight (Prof Andrew Hattersley) R&D 1506105 (04/08/15), REC 14/SW/1152 (03/02/15) 26/08/15 Active 0 2 19
CRF170 GREAT (Dr Suzy Hope) R&D 1503059 (25/09/14) REC 14/SW/1049 (20/08/14) 30/10/14 Closed 21 0 0 0 21
CRF172 DIVA (Dr Bea Knight) R&D 1507116 (18/02/14), REC 14/SW/1140 (30/01/15). NIHR network adopted 04/03/14 Active 19 27 22
CRF175 Transurethral resection of the prostate for cancer diagnosis (Prof Nick Stone)- samples only R&D 5/016 STB016/CTB21 (23/07/14), REC STB016(23/07/14) 16/12/14 Active 9 3 0
CRF178 Effects of Reward on Component Processes of Working Memory (Dr Chris Dodds) UoE Psychology ethics approval (08/10/14) 15/02/15 Closed 0 0 0 0 0
CRF179 TOMMORROW (Dr Joe Butchart) R&D 1504085 (14/11/14), REC 13/SC/0332 (01/07/14).  NIHR network adopted 09/02/15 Closed to recruit- follow up visits only 13 13 1 0 27
CRF180 fATDIVA (Dr Bea Knight) R&D 1508127 (08/05/15), REC 15/SW/0021 29/05/15 Active 4 16 24
CRF181 Accelerated long term forgetting in memory clinics (CI was Alicia Smith, now Dr Craig Newman) R&D 1507110 DPT0288 (DPT approval) (16/09/14), REC 14/SW/0084 (19/06/14) 18/11/14 Active 8 2 8
CRF183 Diabetes prevention using SMS technology (Jane Piper) R&D 1508125 (15/01/15), Westminster REC 12/LO/1322.  NIHR network adopted 02/02/15 Closed to recruitment, FU visits only 10 8 12 0 4
CRF184 Generic genetic typing of Exeter 10,000 R&D PRB37 (18/12/14), 09/H0106/75 (EXTEND ethics) 02/11/2009 18/12/14 Active 325 248 302
CRF185 Influence of dietray nitrate supplementation on cardiac muscle perfusion and vascular function in older people using magnetic resonance techniques-a pilot study (Dr Stephen Bailey) REC 141203/B/19 (Uni of Exeter College of Life and Environmental Sciences) 23/04/15 Closed 10 3 0 0 13
CRF186 DASHER (Dr Andrew Jordan) R&D 1601202 (22/06/15), REC 15/SW/0077 (17/04/15).  NOHR network adopted 13/08/15 Active 0 5 9
CRF187 TRAM (Dr Kash Patel) R&D 1510156 (04/03/15), REC 15/NE/0061 (13/02/15) 04/03/15 Active 11 18 13
CRF188 Fetal Fibronectin (Prof Steve Thornton) R&D 1506096 (10/02/15), REC 14/SW/1151 (08/01/15) 02/03/15 On hold (awaiting amendment) 63 22 0
CRF189 Sputum from cystic fibrosis patients (Philip Mitchelmore) R&D 5/021 STB21/CTB23 (22/04/15), REC 11/SW/0018 (11/04/11) 23/09/15 Active 0 3 17
CRF190 Mesentery tissue (Prof Peter Winlove)- samples only R&D 1204632  (5/022) STB22 CTB24 (22/04/15), REC 11/SW/0018 (11/04/11) 16/06/15 Closed 1 7 8 0 16
CRF191 Monaco (Dr Chris Dodds)

R&D 1511178 REC 15/SW/0076

In set-up 0 0 0 0 0
CRF192 ReTrain (Dr Raff Calitri) R&D 1602209 (26/05/15), REC 15/SW/0074 (02/04/15).  NIHR network adopted 31/07/15 Active 0 3 9
CRF193 MooDFOOD (Prfo Ed Watkins) R&D 1603219 REC 15/SW/0153 NIHR network adopted 28/09/15 Active 0 2 43
CRF194 Cell free fetal resus negative (Jennifer Davies)- samples only R&D 1204632  (5/023) STB23 CTB25 (22/04/15), REC 11/SW/0018 (11/04/11) 18/05/15 Active 18 15 20 0
CRF195 Rectal cancer (Mr Neil Smart)- samples only R&D 1204632 (5/024) STB24 CTB26 (22/04/15), REC 11/SW/0018 (11/04/11)- RDETB REC 04/06/15 Active 4 5 4
CRF196 KARE (DR Celia Morgan) In set-up 0 0 0
CRF197 Approach and avoidance motivation in depression: a combined ESM and fMRI approach (Natasha Bloodworth) REC 2015/894 (13/05/15) 06/07/15 Active 0 50 39
CRF198 Smokeless (Dr Lee Hogarth)

Governance assurance/approval from Northern Devon Healthcare Trust.  15/SW/0199

09/12/15 Active 0 0 1
CRF199 CPinMS (Rick Titball)- samples only 15/NI/0101 (Office for Research Ethics Committees, Northern Ireland (ORECNI) (22/05/15), REC 15/NI/0101 (02/05/15) 22/05/15 Closed 76 0 0 0 76 76
CRF200 The Eye's Mind-variations in the vividness of of visual imagery (Prof Adam Zeman) REC 2014/518 (02/06/15) 12/06/15 Closed 620 46 0 0 666
CRF201 PPPR study (DR Bea Knight) R&D 1510152 (22/04/15), REC 15/SW/0147 (16/06/15) 14/08/15 Active 0 2 4
CRF202 STOPPIT-2 (DR Bea Knight) REC 14/SS/031 Active 0 0 0
CRF203 PANTS-E (Dr Tariq Ahmad) R&D 1307805 (28/08/14), REC 12/SW/0323 (19/08/14).  NIHR network adopted 01/09/14 Active 9 3 6
CRF204 SIDEFX (Gareth Walker) R&D 1507119 (13/05/15), REC 15/SW/0017 (09/03/15) 14/05/15 Active 3 5 1
CRF205 BPA myth and reality (Dr Lorna Harries) REC UEMS 15/70/74 (04/08/15) 14/09/15 Closed 0 104 0 0 104
CRF206 Coagulation Profile analysis (Dr Jason Coppell)-samples only R&D PRB41 (27/08/15), REC 09/H0106/75 (EXTEND ethics) (18/12/14) 24/09/15 Closed 0 50 0 0 50 50
CRF207 The genetics of bipolar disorder and postpartum psychosis (Dr Elaine Green)-data only R&D PRB42 (27/08/2015), REC 09/H0106/75 (EXTEND ethics) (18/12/14) 24/09/15 Closed 0 1700 0 0 1700 0
CRF208 Role of SDC4 and VEGFC in diabetic kidney disease? (Dr Becky Foster)- samples only R&D PRB43 (27/08/2015), REC 09/H0106/75 (EXTEND ethics) (18/12/14) 24/09/15 Closed 0 90 0 0 90 90
CRF209 REJUVENATE (Dr Timothy Etheridge) R&D 1608287 (28/01/16) In set-up 0 0 0
CRF210 Dose-finding of semaglutide administered subcutaneously once daily versus placebo and liraglutide in subjects with type 2 diabetes (Dr Bijay Vaidya) R&D 1604228(04/09/15) or 5/027, REC 15/SC/0380 (22/07/15) 05/10/15 Closed to recruitment 0 0 7 0 7
CRF211 Prostate biopsy collection (Prof Nicholas Stone) R&D 5/027 (11/04/11), REC 11/SW/0018 (11/04/11) 08/12/15 Active 0 0 1
CRF212 Investigating the impact of Mindfulness Based Cognitive therapy (MBCT) on positive affect (Prof Barney Dunn) R&D N/A, REC 13/SW/0137 (13/09/13) 05/11/15 Active 0 0 17
CRF213 IDEAL (Dan Chapman) 15/09/078 (UEMS ethics ctte) (15/10/2015) 02/11/15 Active 0 0 8
CRF214 ImpulsePal: A Feasibility (Samantha van Beurden) R&D N/A (UofE) 15/037/VAN (18/08/15), REC 15/SW/0181  (16/07/15) 17/09/15 Active 0 0 2
CRF215 Brain training to reduce alcohol consumption (Dr Natalia Lawrence) R&D N/A, 2016/1046 (UoE Psychology ethics approval) (23/11/15) 01/12/2015 Active 0 0 6
CRF216 Establishing the assessment of toe perfusion (Prof Angela Shore) R&D 1605244, REC 15/WS0194 30/11/15 Active 0 0 9
CRF217 Wave 4 (Dr Andrew Sharp) R&D 1604227 (30/11/15), REC 14/WS/1014 (20/08/14) Active 0 0 0
CRF218 Diabetes management for mental health service users (Dr Kathleen Mulligan) Noclor reference 179522, East London Foundation Trust (01/12/15), REC 15/WA/0310 (28/08/2015) 25/09/15 Active 0 0 0
CRF219 Identification of novel subtypes of monogenic diabeets by excluding Type 1 diabetes using a polygenic risk score (Dr Kashyap Patel) N/A (Turkish REC) In set-up 0 0 0
CRF220 Sputum from bronchiectisis & cystic fibrosis patients (Dr Philip Mitchelmore) R&D 5/031 STB31-CTB30, REC 11/SW/0018 (RDE TB) (11/04/11) Active 0 0 0
CRF221 Abnormal lipids (Maxine Hough) R&D 1608292 (29/02/16), REC 13/NW/0297 (01/12/13) Active 0 0 0
CRF222 Omental fat (Dr Katarina Kos) R&D 5/032 STB32-CTB31, REC 11/SW/0018 (RDE TB) (11/04/11) Active 0 0 0
CRF223 Vascular and Cognitive Effects of Chronic Polyphenol Supplementation (Joanna Bowtell) R&D N/A (UoE), REC 151021/A/05 (06/01/16) 01/02/2016 Active 0 0 0
CRF224 TriMaster (Prof Andrew Hattersley) R&D 1603221, REC 16/SC/0147 In set-up 0 0 0
CRF225 NIRS for the measurement of haemodynamic markers in bone tissue (Prof Karen Knapp) In set-up 0 0 0 0 0
TOTAL 2206 3505 1532

Non-CRF-managed Studies Using Volunteers from the Peninsula Research Bank

Code

Study Title

Managed by:

CRF116 Physical Activity & Bone Health Sports Science
CRF127 Sit Study Sports Science
CRF136 Weight Loss Intervention Sports Science
CRF139 Does enviornmental quality undermine the psycho-physiological benefits of exercising in nature? Sports Science