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2015-16

Taylor EL, Armstrong KR, Perrett D, Hattersley AT, Winyard PG. Optimisation of an Advanced Oxidation Protein Products Assay: Its Application to Studies of Oxidative Stress in Diabetes Mellitus. Oxid Med Cell Longev. 2015; 2015:496271

 

Siervo M, Lara J, Jajja A, Sutyarjoko A, Ashor AW, Brandt K, Qadir O, Mathers JC, Benjamin N, Winyard PG, Anning C, Shore A, Gilchrist M. Ageing modifies the effects of beetroot juice supplementation on 24-hour blood pressure variability:  An individual participant meta-analysis. Nitric Oxide. 2015 May 1;47:97-105

 

Adingupu DD, Thorn CE, Casanova F, Elyas S, Gooding K, Gilchrist M, Aizawa K, Gates PE, Shore AC, Strain DW. Blood Oxygen Saturation After Ischemia is Altered With Abnormal Microvascular Reperfusion. Microcirculation. 2015 May;22(4):294-305

 

Pilling LC, Joehanes R, Melzer D, Harries LW, Henley W, Dupuis J, Lin H,
Mitchell M, Hernandez D, Ying SX, Lunetta KL, Benjamin EJ, Singleton A, Levy D, Munson P, Murabito JM, Ferrucci L. Gene expression markers of age-related inflammation in two human cohorts. Exp Gerontol. 2015 Jun 16. pii:
S0531-5565(15)00188-6. doi: 10.1016/j.exger.2015.05.012. [Epub ahead of print]

 

Clissold R, Shields B, Ellard S, Hattersley A, Bingham C. Assessment of the
HNF1B Score as a Tool to Select Patients for HNF1B Genetic Testing. Nephron.
2015;130:134-40

 

Clark CE, Aboyans V. Interarm blood pressure difference: more than an
epiphenomenon. Nephrol Dial Transplant. 2015 May;30(5):695-7

 

Locke JM, Wei FY, Tomizawa K, Weedon MN, Harries LW. A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1. Diabetologia. 2015 Apr;58(4):745-8

 

Chakera AJ, Steele AM, Gloyn AL, Shepherd MH, Shields B, Ellard S, Hattersley AT. Recognition and Management of Individuals With Hyperglycemia Because of a Heterozygous Glucokinase mutation . Diabetes Care. 2015; 38(7):1383-92

 

Shepherd AI, Wilkerson DP, Dobson L, Kelly J, Winyard PG, Jones AM, Benjamin N, Shore AC, Gilchrist M. The effect of dietary nitrate supplementation on the oxygen cost of cycling, walking performance and resting blood pressure in individuals with chronic obstructive pulmonary disease: A double blind placebo controlled, randomised control trial. Nitric Oxide: Biology and Chemistry. 2015. 48: 31 – 37

 

Yaghootkar H, Stancáková A, Freathy RM, Vangipurapu J, Weedon MN, Xie W, Wood AR, Ferrannini E, Mari A, Ring SM, Lawlor DA, Davey Smith G, Jørgensen T, Hansen T, Pedersen O, Steinthorsdottir V, Guðbjartsson DF, Thorleifsson G,
Thorsteinsdottir U, Stefansson K, Hattersley AT, Walker M, Morris AD, McCarthy MI, Palmer CN, Laakso M, Frayling TM. Association analysis of 29,956 individuals confirms that a low-frequency variant at CCND2 halves the risk of type 2 diabetes by enhancing insulin secretion. Diabetes. 2015 Jun;64(6):2279-85

 

Clark C, Shore A, Taylor R, Campbell J. 2015. 1C.08: The inter-arm difference in blood pressure and mortality: systematic review and meta-analysis. 33 Suppl 1: e11

 

Goncalves I, Bengtsson E, Colhoun HM, Shore AC, Palombo C, Natali A, Edsfeldt A, Dunér P, Fredrikson GN, Björkbacka H, Östling G, Aizawa K, Casanova F, Persson M, Gooding K, Strain D, Khan F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Kozakova M, Gan LM, Schnecke V, Nilsson J; SUMMIT Consortium. Elevated Plasma Levels of MMP-12 Are Associated With Atherosclerotic Burden and Symptomatic Cardiovascular Disease in Subjects With Type 2 Diabetes. Arterioscler Thromb Vasc Biol. 2015 Jul;35(7):1723-31

 

Affourtit C, Bailey SJ, Jones AM, Smallwood MJ, Winyard PG. On the mechanism by which dietary nitrate improves human skeletal muscle function.  Frontiers in Physiology. 2015 Jul;6

 

Knight BA, Shields BM, Brook A, Hill A, Bhat DS, Hattersley AT, Yajnik CS.  Lower Circulating B12 Is Associated with Higher Obesity and Insulin Resistance during Pregnancy in a Non-Diabetic White British Population. PLoS One. 2015 Aug 19;10(8):e0135268. eCollection 2015. PubMed PMID: 26288227; PubMed Central PMCID: PMC4545890

 

Sansbury FH, Kirel B, Caswell R, Allen Lango H, Flanagan SE, Hattersley AT, Ellard S, Shaw-Smith CJ. Biallelic RFX6 mutations can cause childhood as well as neonatal onset diabetes mellitus. Eur J Hum Genet. 2015 Aug 12. [Epub ahead of print] PubMed PMID: 26264437

 

Jones AG, McDonald TJ, Shields BM, Hill AV, Hyde CJ, Knight BA, Hattersley AT; PRIBA Study Group. Markers of β-Cell Failure Predict Poor Glycemic Response to GLP-1 Receptor Agonist Therapy in Type 2 Diabetes. Diabetes Care. 2015 Aug 4. pii: dc150258. [Epub ahead of print] PubMed PMID: 26242184

 

Chakera AJ, Steele AM, Gloyn AL, Shepherd MH, Shields B, Ellard S, Hattersley AT. Recognition and Management of Individuals With Hyperglycemia Because of a Heterozygous Glucokinase Mutation. Diabetes Care. 2015 Jul;38(7):1383-92. Review. PubMed PMID: 26106223

 

Jenner MK, Gilchrist M & Baker, GC.  Practical considerations in improving research through public involvement. Research Involvement and Engagement. 2015 1:3

 

Lawrence NS, O‘Sullivan J, Parslow D, Javaid M, Adams RC, Chambers CD, Kos K, Verbruggen F. Training response inhibition to food is associated with weight loss and reduced energy intake. Appetite, 2015; 95: 17-28

 

Budd HR, Stokes OM, Meakin J, Fulford J, Hutton M.  Safety and compatibility of magnetic-controlled growing rods and magnetic resonance imaging.  European Spine Journal. 2015 Aug 14.  [Epub ahead of print]. PubMed PMID: 26272372

 

Shore AC, Colhoun HM, Natali A, Palombo C, Östling G, Aizawa K, Kennbäck C, Casanova F, Persson M, Gooding K, Gates PE, Khan F, Looker HC, Adams F, Belch J, Pinnoli S, Venturi E, Morizzo C, Goncalves I, Ladenvall C, Nilsson J.  Measures of atherosclerotic burden are associated with clinically manifest cardiovascular disease in type 2 diabetes: A European cross-sectional study. 2015 Sept 1; 278, 3(291-302). PubMed PMID: 25752315

 

Gaulton KJ, Ferreira T, Lee Y, Raimondo A, Mägi R, Reschen ME, Mahajan A, Locke A, William Rayner N, Robertson N, Scott RA, Prokopenko I, Scott LJ, Green T, Sparso T, Thuillier D, Yengo L, Grallert H, Wahl S, Frånberg M, Strawbridge RJ, Kestler H, Chheda H, Eisele L, Gustafsson S, Steinthorsdottir V, Thorleifsson G, Qi L, Karssen LC, van Leeuwen EM, Willems SM, Li M, Chen H, Fuchsberger C, Kwan P, Ma C, Linderman M, Lu Y, Thomsen SK, Rundle JK, Beer NL, van de Bunt M, Chalisey A, Kang HM, Voight BF, Abecasis GR, Almgren P, Baldassarre D, Balkau B,  Benediktsson R, Blüher M, Boeing H, Bonnycastle LL, Bottinger EP, Burtt NP, Carey J, Charpentier G, Chines PS, Cornelis MC, Couper DJ, Crenshaw AT, van Dam RM, Doney AS, Dorkhan M, Edkins S, Eriksson JG, Esko T, Eury E, Fadista J, Flannick J, Fontanillas P, Fox C, Franks PW, Gertow K, Gieger C, Gigante B, Gottesman O, Grant GB, Grarup N, Groves CJ, Hassinen M, Have CT, Herder C, Holmen OL, Hreidarsson AB, Humphries SE, Hunter DJ, Jackson AU, Jonsson A, Jørgensen ME, Jørgensen T, Kao WH, Kerrison ND, Kinnunen L, Klopp N, Kong A, Kovacs P, Kraft P, Kravic J, Langford C, Leander K, Liang L, Lichtner P, Lindgren CM, Lindholm E, Linneberg A, Liu CT, Lobbens S, Luan J, Lyssenko V, Männistö S, McLeod O, Meyer J, Mihailov E, Mirza G, Mühleisen TW, Müller-Nurasyid M, Navarro C, Nöthen MM, Oskolkov NN, Owen KR, Palli D, Pechlivanis S, Peltonen L, Perry JR, Platou CG, Roden M, Ruderfer D, Rybin D, van der Schouw YT, Sennblad B, Sigurðsson G, Stančáková A, Steinbach G, Storm P, Strauch K, Stringham HM, Sun Q, Thorand B, Tikkanen E, Tonjes A, Trakalo J, Tremoli E, Tuomi T, Wennauer R, Wiltshire S, Wood AR, Zeggini E, Dunham I, Birney E, Pasquali L, Ferrer J, Loos RJ, Dupuis J,  Florez JC, Boerwinkle E, Pankow JS, van Duijn C, Sijbrands E, Meigs JB, Hu FB, Thorsteinsdottir U, Stefansson K, Lakka TA, Rauramaa R, Stumvoll M, Pedersen NL,  Lind L, Keinanen-Kiukaanniemi SM, Korpi-Hyövälti E, Saaristo TE, Saltevo J, Kuusisto J, Laakso M, Metspalu A, Erbel R, Jöcke KH, Moebus S, Ripatti S, Salomaa V, Ingelsson E, Boehm BO, Bergman RN, Collins FS, Mohlke KL, Koistinen H, Tuomilehto J, Hveem K, Njølstad I, Deloukas P, Donnelly PJ, Frayling TM, Hattersley AT, de Faire U, Hamsten A, Illig T, Peters A, Cauchi S, Sladek R, Froguel P, Hansen T, Pedersen O, Morris AD, Palmer CN, Kathiresan S, Melander O,  Nilsson PM, Groop LC, Barroso I, Langenberg C, Wareham NJ, O'Callaghan CA, Gloyn  AL, Altshuler D, Boehnke M, Teslovich TM, McCarthy MI, Morris AP; DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium. Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci. Nat Genet. 2015 Dec;47(12):1415-25

 

Shields BM, Peters JL, Cooper C, Lowe J, Knight BA, Powell RJ, Jones A, Hyde CJ, Hattersley AT. Can clinical features be used to differentiate type 1 from type 2 diabetes? A systematic review of the literature. BMJ Open. 2015 Nov 2;5(11):e009088. PubMed PMID: 26525723; PubMed  Central PMCID: PMC4636628

 

Sansbury FH, Kirel B, Caswell R, Lango Allen H, Flanagan SE, Hattersley AT, Ellard S, Shaw-Smith CJ. Biallelic RFX6 mutations can cause childhood as well as  neonatal onset diabetes mellitus. Eur J Hum Genet. 2015 Dec;23(12):1744-8. Epub 2015 Aug 12. PubMed PMID: 26264437.

 

Richard A. Oram, Timothy J. McDonald, Beverley M. Shields, Michelle M. Hudson, Maggie H. Shepherd, Suzanne Hammersley, Ewan R. Pearson, and Andrew T. Hattersley, on behalf of the UNITED Team    Most People With Long-Duration Type 1 Diabetes in a Large Population-Based Study Are Insulin Microsecretors. Diabetes Care 2015;38:323–328. doi: 10.2337/dc14-0871. PMID: 25519449

 

McDonald TJ, Oram RA, Vaidya B. Investigating hyperkalaemia in adults.  BMJ 2015; 351