Application to use CRF

Please apply to the Clinical Research Facility in the following circumstances:
a)   you are in the early stages of protocol development and you would like help with
      experimental design, protocol development and research governance.
b)   you have a funded, approved study that you would like to carry out in CRF space or with CRF
c)   you would like to use samples/data held by the CRF or would like the CRF to facilitate a collection of spare clinical samples under their RTB ethics. See our Tissue Bank page for how to apply
How to apply for CRF support
Please contact the CRF Manager,, to discuss your needs.   The process for formal application is detailed below. 
1. Complete an initial request for CRF support and return this to
2. Once you have the details of your protocol meet with relevant Nursing Manager ( for intensive vascular studies and MRI or for metabolic, community and large cohort studies) to Complete Intensity Tool .  This will calculate the number of hours of nurse/technician/MRI time that you need and will help you think through the practicalities of the project.  The intensity tool will also provide you will a cost for this time if you need this inforamtion ahead of a funding application.
3. To calculate the cost of Biochemsitry on your project please complete pathology costing form avail;able from the RD&E biochem department.  If your project is adopted by the network you may be able to getting screening biochemistry costs or tests that would normally be carried out as part of clinical care covered as Service Support Costs.
4. Transfer information from the intensity tool and pathology costing form into the  CRF Feasibility Form.  This form requires CRF manager authorisation before local R&D approval can be given.  The feasibility form will be approved on the basis of the ethically approved protocol and must be updated and re-approved after every major protocol amendment to ensure that CRF support for the project is maintain at sufficient levels.
5.  If your project requires freezer space please complete the "Application to Store Samples" form and discuss the practicalities of samples storage and transport with Gillian Baker or Marcus Mitchell.  Please be advised that the CRF cannot store patient-identifiable samples within research freezers.  Samples must be labelled with a code that can be readily linked to the patient's consent for samples to be used and stored for research purposes.
6. The CRF can assist with NIHR adoption and ethics advice, so please do not hesitate in contatcing us if you have any queries.